Tuberculosis coinfections HIV/AIDS in Africa

workshop on hiv/aids , tuberculosis in south africa.

much of deadliness of epidemic in sub-saharan africa caused deadly synergy between hiv , tuberculosis, termed co-epidemic . 2 diseases have been inextricably bound since beginning of hiv epidemic. tuberculosis , hiv co-infections associated special diagnostic , therapeutic challenges , constitute immense burden on healthcare systems of heavily infected countries ethiopia. in many countries without adequate resources, tuberculosis case rate has increased 5 ten-fold since identification of hiv. without proper treatment, estimated 90 percent of persons living hiv die within months after contracting tuberculosis. initiation of highly active antiretroviral therapy in persons coinfected tuberculosis can cause immune reconstitution inflammatory syndrome worsening, in cases severe worsening, of tuberculosis infection , symptoms.

an estimated 874,000 people in sub-saharan africa living both hiv , tuberculosis in 2011, 330,000 in south africa, 83,000 in mozambique, 50,000 in nigeria, 47,000 in kenya, , 46,000 in zimbabwe. in terms of cases per 100,000 population, swaziland s rate of 1,010 far highest in 2011. in following 20 african countries, cases-per-100,000 coinfection rate has increased @ least 20 percent between 2000 , 2011: algeria, angola, chad, comoros, republic of congo, democratic republic of congo, equatorial guinea, gambia, lesotho, liberia, mauritania, mauritius, morocco, mozambique, senegal, sierra leone, south africa, swaziland, togo, , tunisia.

since 2004, however, tuberculosis-related deaths among people living hiv have fallen 28 percent in sub-saharan africa, home 80 percent of people worldwide living both diseases.